Cvgbear From United States of America, joined Apr 2004, 39 posts, RR: 0
Reply 3, posted (10 years 1 week 4 days 2 hours ago) and read 1104 times:
According to CVG's website, there is no actual date/airline, but I did find that the first commercial flight landed in 1947 from CLE operated by Boone County Airline. International arrivals terminal was built in 1978 and Delta made it a hub in 1981.
While it's not the answer to your question, I would venture to say that it probably was Delta in the early 80's.