For hotel rooms, nothing beats the accomodations at the Venetians. Great rooms (every single one is a suite), at excellent prices. Service is friendly, and overall quality is five stars.
For gambling, the Mandalay Bay is the place to go, so I've heard.
For shopping, the best place is the Venetian and Alladin, with two large indoor shopping centers. Yet you don't feel crowded, because they have superb designs.
For dining, the Venetian tops them all, with a large variety of international cuisine (delicious real
Mexican food) and cheaper, fast food type restaurants.
For fun and games, Excalibur is the place to go. With the great family fun center downstairs, at a reasonable price, you can have tons of fun. Also, they have a great Medival jousting show, with great food.
For airport views, nothing tops the Luxor, with an unobstructed view of the airport from the side of the pyramid which faces it.
Overall, Venetian tops them all in my opinion, overall just a splendid, well designed, beautiful hotel.
Hope I didn't miss anything.