oly720man
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Autism An Autoimmune Disease? Novel Treatment.

Thu May 12, 2011 10:32 am

Being on the mailing list, I got this today

http://articles.mercola.com/sites/ar...mmation-play-a-role-in-autism.aspx

Researchers have found that the most striking differences between autistic and normal brains were loss of the purkinje cell layer in the cerebellum, and also activation of the microglia, which are cells that are central to the inflammatory response.

The inflammatory response is your body's defense against invasion, but in autism, it seems to be turned against itself. It seems there is an inflammatory war going on in the brains of autistic children and adults.


Reading around I came across this blog

http://autismtso.com/about/the_story/

about a boy whose symptoms and behaviours all disappeared when he'd been badly bitten by chigger mites, but reappeared when the immune reaction to the bites wore off as they faded. This led his father to wonder whether his autistic symptoms were due to some form of immune response because, also, his behaviour deteriorated when he had allergies.

He's now undergone a TSO treatment, the use of whipworm eggs, something that has been used successfully in treating ulcerative colitis and Crohn's disease, as a means of giving the immune system something genuine to do and it's proved very successful.

The summary

After 14 years of observing my autistic son and researching the topic, I formed the hypothesis that the most difficult symptoms of autism (including self abusive behavior, compulsivity, anxiety, behavioral inflexibility, etc.) are the result of an aberrant immune response. I researched ways to down-regulate the immune system and came to TSO, a living organism being used successfully to treat other autoimmune disorders. After preparing a research paper showing this hypothesis was supported by the medical literature, I presented it to my son’s doctor and we began treating my son with TSO. After 10 weeks he completely lost all symptoms of agitation, agression, self abusive behavior (including head smashing and hand biting), perseveration, behavioral inflexibility, compulsivity, impulsivity, repeated questioning, “stimming” and hypersensitivity to external stimuli. He continues to take TSO every two weeks and the symptoms have been gone now for 15 months.

Further, this treatment is being looked at for treating multiple sclerosis

http://www.ncbi.nlm.nih.gov/pubmed/21372112

Probiotic treatment strategy based on the hygiene hypothesis, such as administration of ova from the non-pathogenic helminth, Trichuris suis, (TSO) has proven safe and effective in autoimmune inflammatory bowel disease. Objective: To study the safety and effects of TSO in a second autoimmune disease, multiple sclerosis (MS), we conducted the phase 1 Helminth-induced Immunomodulatory Therapy (HINT 1) study

Hope for the future in some very debilitating illnesses?
wheat and dairy can screw up your brain
 
FingerLakerAv8r
Posts: 251
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RE: Autism An Autoimmune Disease? Novel Treatment.

Thu May 12, 2011 12:38 pm

I have read a vast number of articles about how stimulating the immune system has improved the prognosis and lives of people affected my a good number of diseases and syndromes.

Interesting article.
 
oly720man
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RE: Autism An Autoimmune Disease? Novel Treatment.

Thu May 12, 2011 2:21 pm

Quoting FingerLakerAv8r (Reply 1):
I have read a vast number of articles about how stimulating the immune system has improved the prognosis and lives of people affected my a good number of diseases and syndromes.

There have certainly been a number of reports about how being too clean is potentially bad because of immune systems going haywire, but it makes you wonder how many health conditions are exacerbated, if not wholly caused, by this.

Maybe household cleaning products should only kill 50% of germs rather than 99.9%.
wheat and dairy can screw up your brain
 
TSS
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RE: Autism An Autoimmune Disease? Novel Treatment.

Thu May 12, 2011 5:57 pm

Quoting oly720man (Reply 2):
There have certainly been a number of reports about how being too clean is potentially bad because of immune systems going haywire, but it makes you wonder how many health conditions are exacerbated, if not wholly caused, by this.

As someone who deals with the general public on a daily basis, I can tell you that there certainly seem to be a lot more aggressively germ-phobic people around now than there were only a few years ago. The funny thing is, a lot of them seem to be obsessive about only one possible source of contamination while ignoring all others. Cases in point:

1. One lady insisted that all her grocery purchases, including unpackaged fresh fruit, be placed in the main part of her shopping cart with no products in the child seat for fear that the child seat might previously have held an infant with a leaky diaper    ... conveniently ignoring how many fluid-leaking packages of raw pork and chicken products had been placed in the main basket since the store opened that day.   

2. At a store where purchases are normally transferred from one shopping cart to another as they're rung up, one lady insisted that all her purchases be placed back in her original cart because she had already "sanitized" it and didn't want to have to "sanitize" another one... which seemed reasonable until she paid her bill IN CASH!    Anyone care to speculate on in how many stripper's G-strings or up how many recreational drug user's noses those bills had been stuffed before that lady got them? While the possibility might exist that she had "sanitized" her folding money as well as her shopping cart, the lady I'm describing placed her change right back in her wallet alongside the bills already in there, thus negating any "sanitizing" she might have done.   
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DocLightning
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RE: Autism An Autoimmune Disease? Novel Treatment.

Thu May 12, 2011 6:29 pm

People have been waiting for me to say something intelligent.

Sorry to disappoint, but I have little to say. Reading over this stuff, it's possible, but I haven't seen much mainstream research to back it up.
-Doc Lightning-

"The sky calls to us. If we do not destroy ourselves, we will one day venture to the stars."
-Carl Sagan
 
oly720man
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RE: Autism An Autoimmune Disease? Novel Treatment.

Thu May 12, 2011 8:17 pm

Quoting TSS (Reply 3):
The funny thing is, a lot of them seem to be obsessive about only one possible source of contamination while ignoring all others

Perhaps a little ironic given that obsessions can be one of the manifestations of autism.

http://www.autism.org.uk/en-gb/livin...itive-behaviours-and-routines.aspx

I know what you mean though. People will respond to the latest scare story and believe the adverts. Shopping trolleys are dirty, but no mention of the air, door handles, loose change, other people, etc, etc. And they'll go home and kiss the cat that 5 minutes earlier was licking its backside.


Elsewhere, I don't know how your shopper sanitized her trolley, but

http://sanitizeshoppingcarts.com/arc...tizer-installed-at-giant-eagle/146

Recognizing a need in the sanitization industry for a quick, easy-to-use product- several states are passing federal mandates requiring sanitization of of shopping carts- NewTec began work on the system about nine months ago, originally focusing on a chemical water product, Gainor said.
wheat and dairy can screw up your brain
 
Maverick623
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RE: Autism An Autoimmune Disease? Novel Treatment.

Thu May 12, 2011 8:35 pm

Quoting oly720man (Reply 5):
several states are passing federal mandates

        
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AustrianZRH
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RE: Autism An Autoimmune Disease? Novel Treatment.

Fri May 13, 2011 8:22 am

Quoting TSS (Reply 3):
I can tell you that there certainly seem to be a lot more aggressively germ-phobic people around now than there were only a few years ago.

When I was a child of four to seven, I sat in the sandbox on the playground, ate my share of dirt and drank probably gallons of untreated water from the Lake of Constance.

When I went near the lake on Easter weekend, the sandbox on the playground was empty and mothers were actively restraining their kids from going there because it's oh so dirty and germ-infested. What happened to being allowed to be a child in the last decade? That whole thinking that we should live only in disinfected and sanitized places is ridiculous.
WARNING! The post above should be taken with a grain of salt! Furthermore, it may be slightly biased towards A.
 
oly720man
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RE: Autism An Autoimmune Disease? Novel Treatment.

Fri May 13, 2011 9:11 am

Quoting AustrianZRH (Reply 7):
were actively restraining their kids from going there because it's oh so dirty and germ-infested.

Well, there is one condition, toxocariasis, that could lead to blindness if left untreated, but that relies on infected dogs using the sandpit, or playground, as a toilet

http://www.nhs.uk/conditions/Toxocariasis/Pages/Introduction.aspx

but, yes, in general we do have an immune system, developed and honed over hundreds of thousands of years, or more, that should deal with most things quite happily.

I blame the advertisers.

Before we had household germs to kill we never knew they were there.
wheat and dairy can screw up your brain

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