VG Airlines is planning to start out with service to New York (JFK) starting on March 1, followed by Boston (BOS) on March 15th.
Then a 3rd destination will follow, most likely Los Angeles (LAX). No date announced yet though.
They are also looking into serving Denver (DEN). A BRU-DEN flight could do great if they do some sort of code-share agreement with United on that route. If not, then I'm not sure how well it will do. It might have a chance.
That is all that they have announced so far. I'm sure they will look at other destinations such as SFO, MIA, ATL, etc.
I'll miss Sabena.
"Generosity is giving more than you can, and pride is taking less than you need." - Khalil Gibran