I remember when DL pulled out of MGM a couple of years ago. They were reeling, then being known as the largest city in the US without mainline service. (With all of the shakeups lately, I'm not sure if that is the case.)
HSV is close to being on that list, although I don't think we ever will be. We had 17 mainline between DL, AA, and US in 1999, now down to 7 between AA and DL. But that is the national trend.
DCU (Decatur, Alabama) used to be served by Southern Airways until 1967 when HSV opened at its present site. IT's last flight was to MSL, in fact. I'm not completely sure, though, that these were run with jets, so it may not completely fit into this thread. (I don't know if Southern even had jets way back yonder...)
Rogue TRader is correct in saying that the Southern Airways flight number 242 originated
at MSL, but that leg of the flight departed HSV. It remains the only fatal commercial crash from HSV at its present location.
Anyone have anymore info on the DCU flights?
Nature forms us for ourselves, not for others; to be, not to seem.