Even 3-3-3 isn't that bad on the A330, compared to 2-4-2 on a 767. I've also done 3-3-3 in a MON A300 and that wasn't too bad. The AIH 767-300ER was the worst, terrible leg room and terrible seat width
I hope I don't have to fly them again (in the majority of cases we can fly scheduled, but never want to fly from LHR for some crazy reason..).
I don't like the idea of 2-5-2, the 5 annoys me, I hate a row that has too many seats without an aisle. I think that 2-4-3 is the best option, unfortunetely it doesn't look that 'balanced'