Whenever I rent a plane, usually a C172, one of the big things for me that separates a good plane from a crappy one is trim stability. My favorite 172 that I flew for most of my PPL training was great: you could trim takeoff, trim for cruise, and then adjust for landing and that was it. And I would almost never touch it any other time because it was so stable. There was another plane the instructors liked and I hated because the trim was ultra-sensitive. At cruise, it was like flying parabolas the whole time trying to find the perfect trim setting.
My questions is to those of you who fly the big rigs: do large airliners (B737 on up) vary individually like C172s/152s in terms of trim stability? Are particular planes, say within the company MD-80 fleet, really easy to fly in terms of trimming the airplane while another one requires a lot of attention?
To you all, what else besides trim differentiates a good plane to fly versus a bad one?