World Airways operated HNL/OAK/LAX/BWI/EWR/LGW/FRA in the 80's.
TransAmerica operated from OAK to SNN/BRU I believe.
Capitol operated from LAX to JFK and one or two European destinations at one point.
Air Florida operated to Europe from Florida.
Loftledier/Icelandair was once a transatlantic LFC.
America West operated to Honolulu and Nagoya.
Wardair operated Canada to Europe.
Coast to Coast and Border to Border, Ozark Flies YOUR Way!