If you live in the US, you can fly direct and non-stop from LAX with QF or NZ.
South America with LAN Chile or Aerolineas Argentinas.
From Asia and Europe, there are direct choices with CX, SQ, QF, NZ et al!
There are a number of choices from Africa too!
For most people, it's a very long haul, so how would you choose to get here?