Currently World Airways operates to Luanda Angola from Houston a couple times a week. The flights which operate under the Sonair banner have been flying for several years carrying oil industry types back and forth. The aircraft is equipped in a 2 class configuration, not the typical World Airways cattle car MD-11 set up. World also tried operating its own scheduled service flights to Johannesburg back in the mid-90s however the experiment was dropped quickly.
Indeed TWA also operated to Africa. Actually Cairo was one of its first destinations to be served via Paris shortly after WWII. Cairo managed to stay on TWAs route map until the very end having been operated with B767-300s nonstop from the JFK with continuation service to Riyadh Saudi Arabia. If I'm not mistaken the carrier also might have operated to Morocco for a brief period.
Pan Am used to serve Africa quite a bit. In the 80s Monrovia, Johannesburg, Lagos and Nairobi were served. Jo-burg was dropped as part of US sanctions against South Africa. Nairobi was served pretty close to the end of the carrier finally with A310s via Frankfurt. Pan Am in addition served a few other African destinations back in the 60/70s with B707s.
In addition there was short lived upstart airline US Africa Airways with 2 leased American MD
-11s based at Washington Dulles.
Lastly, I believe Continental Airlines is due to start EWR
-Lagos service in 2005. They had applied with the DOT a few months back for the route.
[Edited 2004-12-02 09:02:01]