I would work on getting your degree. In general, the regionals aren't going to require a degree to be hired. The majors/legacies/LCC's on the other hand, have their pick of pilots out there today and can (and often do) use it as a screening tool. That is not to say that you won't be able to get a job at the majors without one, but the companies may decide that they won't look at you without one.
You should be able to have a reasonable lifestyle as a captain at most of the regionals but understand that end of the market doesn't lend itself well to a long stable career. There are forces at play pitting one against the other in the pursuit of new and continued business and the 'players' of today may be the Comair's of tomorrow (not a swipe against Comair-- a statement of management's using the BK process to force concessions and at the same time watch the flying being peeled away). Today, Skywest is doing well, Republic Airways Holdings (RP, S5
) is doing well, and Mesa is doing well and adding business and growing. Tomorrow, that could change. Look at Atlantic Coast 5 years ago. WHere are they today? Look at Air Whiskey 5 years ago. Totally different bases (do you want to move?) and new partner.
I am not saying the majors are stable-- look at the turmoil and tumult over the last 5 years. The difference is that the majors control their own flying and aren't forced to bid for their partners flying every few years.
Your questions about Comair:
1. Travel benefits: you will get them on Delta. They are pretty good.
2. Yes, you would be able to fly pretty much any of the routes through their route network.
3. See above. Get the degree-- it doesn't necessarily matter in what. Just get it and don't let them use your not having one as a screening criteria.