I love the MD-80 to death, mostly because of its design being a welcome departure from the norm. The size of the rear-placed engines, the T-tail as well as the length fascinates me. I'm one who loves the noise of aircraft and although the MD-80 isn't the loudest, the power (as Lauda777 said) is awesome.
The seating configuration is great and I love the inclination of climb (although not as great as the DC-9, but that also depends on the pilot as well). After take-off, it's great to be inclined back in your seat and see the class-dividing wall WAY up in the air.
As far as I know, it has a very good safety record. The longest flight I've done in the MD-80 is 3h45m and the shortest, about 12mins.
It's one of my favourite type of aircraft.
I hope you enjoy your trip on one such example.