The Howard Hughes HK-1 (Spruce Goose) Flying Boat. It dwarfs a Boeing 747. It is currently housed at the Michael King Smith Aviation Museum in McMinnville, Oregon. It has a 320 foot wing span, is 218 feet long, and is 30 feet wide. The wing is over 11.5 feet thick. Its gross weight is 300,000 lbs. It flew only 1 time, in 1947. I don't know if its the largest plane ever built, but it sure is enormous.
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