The models are fairly consistent with Irene heading up the coast of the eastern U.S. Let's hope she stays as far east as possible and causes minimal damage along the way. That being said, airlines can't afford to just hope she stays away.
WIth EWR and JFK being major, international airports, she will most likely disrupt a lot of flights. It looks like a Sunday event in the NYC and New England area. So, how much will this affect everything? As in, will the flights just stay at their locations and "skip" a day or two? How does this affect crews? Is it as simple as an extra day in a hotel? What about the aircraft, many will stay away, but many will also have to be ferried somewhere, how far away from the area will they be flown?
Then there is TEB, ISP, PVD, BOS, MAN and the list goes on.