Yes this does make sense, and it would not surprise me in the least if Cathay Pacific ordered a few 747-400LR's (maybe 5 for a starting order).
But in my opinion I bet you CX will also order the A380, which when it arrives (if ordered) in say late 2006 or early-to-mid 2007, would be placed on routes where conditions are restricted (time windows, route permissions).
Cathay is wonderful at being able to operate both types of aircraft so efficently and to quell Boeing vs. Airbus fights on this forum (although the latter is a side effect, as if CX would care about the fights on this forum) and being a member of the wonderful one
world alliance just makes it that much better
Head in the clouds... yet feet planted firmly on the ground.