Boston definitely is one of the nation's largest num-hub airports, as Delta, American, US Airways, and to a small extent United all operate minihubs out of Logan. There's also the countless airlines that operate shuttles to the major business markets, as well as nearly every European airline out there flies to the Bay Area.
New York JFK is also a large non-hub airport. Delta, TWA, United, American, and British Airways all have sizeable operations. Many third-world airlines(pardon the phrase, but there was none that I could think of) like Biman Bangladesh, Pakistani, and Royal Air Maroc fly to JFK, and most European airlines fly multiple daily flights to the capitals of Europe.
Los Angeles and San Francisco are both dominated by the Big Three, them being Delta, United, and American. They all have numerous daily flights to Hawaii and the Pacific business centers. Both airports have widebody flights to the East Coast business centers.
Honolulu, HI is also a largely non-hub airport, although Hawaiian and Aloha are both based there. They tend to only operate shuttle flights within the Hawaiian Islands and a few flights to the West Coast. These don't really compare to the widebodies flown by major American and Asian airlines to Honolulu.