Most airliner antiskid systems incorporate a "touchdown protection" mode. This function (generically speaking), while airborne with the gear down, "dumps" all brake pressure either if the pedals are depressed or parking brake set prior to touchdown. Initial wheel spinup would occur, in other words, the brakes shouldn't be "locked" on touchdown.
After touchdown wheel spinup, when the touchdown protection mode deactivates, the brakes would probably lock (with the parking brake set scenario) because setting the parking brake deactivates the antiskid system.
You're only as good as your last departure.