Under US rules:
200 knots to 3000'
250 knots to 10000'
Above ten thousand, let the machine decide what it wants. It may vary between about 290K to as high as 340K.
One technique is to climb at high vertical speed into tailwinds aloft, and at high forward speeds if the winds enroute are headwinds. This can be done either by selecting a speed/mach or by selecting a higher or lower cost index on the performance page. The reasoning behind this is that if you are going to have tailwinds, you want to get up into them as soon as possible. On the other hand if you are going to have headwinds at cruise you should not be in such a hurry to encounter them and might as well make headway during the climb.
Happiness is not seeing another trite Ste. Maarten photo all week long.