Hmmm....I never really thought about the fact that all 3 NYC airports have 4/22s. BOS
also does. That's 7 4/22s out of 14 runways in NYC and BOS
I wouldn't put too much emphasis on the "north/south" or "east/west" part. Those are just convenient ways to refer to and distinguish the runways from each other, as far as I know.
I would guess that in designing an airport, you'd want to align the runways with the prevailing winds, but I'm sure there are plenty of compromises, especially when considering how much land you have available (and what shape the land is), possible flight paths (noise abatement), obstacles, etc.
I'm watching Jeopardy. The category is worst Madonna songs. "This one from 1987 is terrible".