Flying IFR, you are unlikely to notice anything different at all, as Canadian ATC is exactly the same as American ATC. You'll go from Cleveland Center to Toronto Center to Cleveland Centre just like you were flying in the States.
On the two examples you mention lost comms and cruising altitudes, there is little difference.
The only slight difference I have noticed between FARs and CARs involves takeoff/landing minima, takeoff alternates and destination alternates, and as you are not actually landing in Canada these will have no bearing on your flight.
For your reference:
Just because I stopped arguing, doesn't mean I think you are right. It just means I gave up!