2 months ago I was on a 2-5-2 Malaysian 777, on a long night flight KUL-AMS. I had one of the aisle seats of the 5 seater.
I would rather have had that middle seat. A couple sitting next to me had to get out at least 2 times each during the night, I had to wake/stand up at least 8 times (also when one of them returned back to her/his seat).
Photo © Jason Milligan
Great PTV, legroom and crew but no sleep, on this 22 hours trip (that started at Brisbane). Wouldn't you prefer a middle over an aisle seat on a night flight, given the choice ?