Cockpit
Programs are ongoing with airlines and authorities to enable reduced crew (single pilot) during stages of flight. Communication systems, cockpits, crew rests and even lavatories would be adjusted to ensure enhanced monitoring and awareness is created for all involved. https://www.flyingmag.com/story/news/ca ... ong-hauls/
Engines
Following contract extension with RR, new engine technology matures, new fan technology, gearboxes and materials being tested. https://www.rolls-royce.com/media/press ... ecord.aspx
Cabin
New cabin technologies which could be featured in the future in all Airspace cabins, are tested on a A350 for development and certification purposes. https://www.airbus.com/en/newsroom/news ... t-aircraft
New derivatives
Freighter. Airbus is actively promoting a A350-950F freighter variant, a 100t~, the first all composite freighter I guess. EIS is foreseen in 2025 and we might hear more next week in Dubai. https://www.flightglobal.com/programmes ... 81.article
Capacity. Over the years Airbus looked at stretching the A350, to a 400 seat 777-9 competitor. This development was shelved in recent years, with other priorities prevailing. But would be restarted if demand recovers for large widebodies in a few years. Meanwhile capacity improvement programs are commencing (new galleys, lav's) https://www.executivetraveller.com/airb ... -a350-2000
Payload-Range Demand for additional payload-range seems present in Qantas' upcoming Sunrise A350 order. A350 would connect Australia East Coast to US East coast and Europe. A higher A350 MTOW would enable enhanced capacity, payload, range or a combination. https://edition.cnn.com/travel/article/ ... index.html

source: keesje
It seems in the second half of this decade we slowly see an A350 Next Gen production standard evolving from all ongoing developments, consolidating marketshare in the central 300-350 seat long haul segment. Still many A330s, A340s and 777s will come up for replacement this decade and worldwide government show a reduced flexibility towards aircraft emissions.