I looked up one of the old press releases from RDU
Airport Authority about the top ten destinations for Mainline and Regional destinations feasible for daily service they are as follows. (From Winter of 2011)
"The study determined that the following cities should be priorities for the airport to establish mainline (large) jet service.
Fort Myers, Fla.
Salt Lake City
The following cities were identified as priorities for the establishment of regional (small) jet service:
West Palm Beach, Fla.
In evaluating the development of additional non-stop international service from RDU
, the study determined that in order for a route to be successful, it would require service to a city that would allow for connections to additional destinations.
The study noted that it is feasible for RDU
to pursue the establishment of an additional transatlantic gateway through Paris, Frankfurt or Munich. These would need to be developed in conjunction with one of the major air carrier alliances, such as SkyTeam or Star Alliance.
Another possible region for international service is the Caribbean. San Juan, though part of the United States, could provide a strong gateway for Caribbean connections. Additional service to Cancun or Punta Cana was determined as feasible."
It will be interesting to see how many of these destinations actually come to frutation.