How do you go about doing a new edit? Start from scratch with the original, and be careful about the points already mentioned, especially the sharpening and noise.
It's a hard balance to get right at first, as sharpening leads to noise, and noise reduction leads to softness. All I can say is, pick your spots to sharpen and 'de-noise', as applying blanket sharpening and noise reduction to the whole image is not going to help (this is also known as using 'selective' sharpening).
If you have any more specific questions, fire away.